The human body has many natural barriers intended to prevent microorganisms, diseases, and toxins from making it into the body. The mucus membranes of the respiratory, gastrointestinal, and female...
By harnessing the power of regeneration residing in our own bodies, stem-cell therapies have transformed science fiction into reality. Already they have repaired damaged hearts, restored vision to...
The scientists and physicians invited to the April 12, 1955, meeting at the University of Michigan in Ann Arbor to hear the results of the 1954 field study on the polio vaccine created by Jonas Salk...
Developing a malaria vaccine is a particularly knotty problem: Vaccines typically can target only one or a few antigens—proteins produced by infectious organisms, against which the host’s immune...
About one in five prescriptions is “off label”—that is, a drug prescribed to treat a condition for which it hasn’t been approved by the Food and Drug Administration. That’s a legal option for...
Nearly every major hospital or cancer treatment practice performs specific genomic testing on every cancer patient’s tumor sample — such as K-ras oncogene analysis for those with colorectal cancer or...
In this era of cancer genetics, we’ve come to think of cancer as something like a car. Runaway cell proliferation is driven by accelerators, or oncogenes, that are stuck on go—in collusion with...
The challenge posed by Alzheimer disease (AD) is stark: If no means of preventing or delaying AD is identified, the number of Americans suffering from the disease is projected to rise from 5.3...
I t’s a sad fact of modern medicine that many diseases—cancer, Alzheimer’s, Parkinson’s—remain difficult to treat. But for many of the most prevalent disorders, chronic diseases that affect large...
Mapping biochemical information in the brain has the potential to unlock the biochemical processes involved in neuropsychiatric disorders, which remain poorly understood. Although techniques such as...

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