Massachusetts General

A drug approved for the treatment of rheumatoid arthritis may also turn out to be the first targeted therapy for one of the most common forms of kidney disease, a condition that almost inevitably...
Being part of the Mass General Research Scholars Program has helped Galit Alter, PhD, advance her work and attract the attention of major funding agencies.
At Massachusetts General Hospital, scientists have long understood the potential of egg freezing for women who want to preserve their fertility.
Like many innovations in medicine, this discovery began as a problem. In the early 1990s, radiologists began using positron emission tomography, a type of body-scanning technology, to hunt for...
A search for genes that change their levels of expression in response to starvation has uncovered potential clues to the mechanism behind the health benefits of omega fatty acids. MGH researchers...
Throughout the month of February, our doctors and specialists in the Massachusetts General Hospital Institute for Heart, Vascular and Stroke Care will be sharing their expertise on various heart...
Anne Louise Oaklander, MD, PhD, associate professor of Neurology, says shingles and post-herpetic neuralgia (PHN), a serious neurological complication in which pain lingers in an area of previous...
About half of a small group of patients with fibromyalgia – a common syndrome that causes chronic pain and other symptoms – was found to have damage to nerve fibers in their skin and other evidence...
More than one in 10 Americans takes one or more antidepressant medications, and for that large chunk of the population, recent events surely have been unsettling. Three books published in 2010 were...
Watching Wyatt Joyner wiggle and bounce in his mom’s lap, it is difficult to imagine that the 9-month-old – now nearly the size of his 2-year-old sister – was once in the Newborn Intensive Care Unit...
A team of surgeons, audiologists and nurses from the MGH and Massachusetts Eye and Ear Infirmary recently performed an auditory brainstem implant (ABI) on a 16-month-old patient – the youngest person...
Harry Orf, PhD, is determined to make it easier for internal and external audiences to fully grasp the breadth and impact of MGH research.
Reisa Sperling, MD, is using neuroimaging to ask whether anti-amyloid antibody treatment can reverse Alzheimer’s disease pathology before memory loss sets in. “We are going beyond looking for...
It has been more than 20 years since the Association of American Medical Colleges last revised its Medical College Admission Test. The MCAT has traditionally focused on basic scientific concepts—...
Researchers from the Massachusetts Eye and Ear Infirmary, The Children's Hospital of Philadelphia, Loyola University Chicago Health Sciences Division and their collaborators have isolated an elusive...
The enteric nervous system (ENS) is an intricate network of neurons and glial cells present in the wall of the intestine and responsible for regulating critical functions of the gastrointestinal (GI...
Although legally permitted to drive in the US, people with partial central vision loss (blind areas) in both eyes, due to stroke, or other types of traumatic brain injury, may have difficulty in...
MGH researchers have discovered a type of mutation known as copy-number variants – deletions, duplications, or rearrangements of human genomic DNA – in affected members of 10 families with early-...
A 72-year-old patient is losing weight. His primary care provider believes the cause may be a stomach virus he recently contracted, but it is hard to be certain – the weight loss has been gradual,...
Q&A with Ozanan Meireles, MD Q: What is type 2 diabetes? What is prediabetes? Type 2 diabetes is a chronic, degenerative disease that develops when the body cannot make enough, or properly use,...
A phase I clinical trial has confirmed that use of a generic vaccine to raise levels of an immune system modulator can cause the death of autoimmune cells targeting the insulin-secreting cells of the...
Mark Albers, MD, PhD, is developing a set of simple but powerful tools that examine the cognitive processing of odors to screen for the very earliest stages of preclinical Alzheimer’s Disease. “...
New research indicates that a disruption of brain signals for reward and punishment contributes to increased pain sensitivity, known as hyperalgesia, in fibromyalgia patients. Results published in...
Imagine not being able to feel pain or cold, not being able to swallow and needing an oxygen tank to fly in a plane. Imagine crying without producing tears. Children who have a rare disease called...
People are increasingly looking for herbal and natural remedies to treat depression. Among some of the more popular and better studied natural remedies are St John’s Wort (SJW), S-adenosyl methionine...
Transcending the disciplines of microbiology, molecular and cell biology, and physiology, Dr. Alessio Fasano’s research focuses on the mucosal biology of the gut. By focusing on the “cross talk”...
A team led by MGH researchers has identified a genetic signature that may reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer. If confirmed, the genetic risk...
The initial assessment of a blood test to help diagnose major depressive disorder indicates it may become a useful clinical tool. A team including MGH researchers reports that analyzing levels of...
Specially designed comprehensive behavioral therapy is more effective than sessions offering patient support and education in helping adults with Tourette syndrome manage their tics – sudden,...
Bioengineered rat kidneys developed by Massachusetts General Hospital (MGH) investigators successfully produced urine both in a laboratory apparatus and after being transplanted into living animals...

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