Massachusetts General

Recent work at the MassGeneral for Hospital Children’s Developmental Immunology Program reveals potential therapeutic targets for staph-related infections, inflammatory bowel disease, Alzheimer’s...
Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate...
As the nation’s healthcare system strains to manage a sour economy and an aging population, large academic medical centers like Massachusetts General Hospital are on the hot seat to cut costs. In the...
BOSTON – For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what...
The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis – blocking production of a mutant protein that causes an inherited form of the progressive neurodegenerative...
MGH investigators have determined that one of the recently identified genes contributing to the risk of late-onset Alzheimer's disease regulates the clearance of the toxic amyloid beta (A-beta)...
Thomas Gagnon arrived at Massachusetts General Hospital expecting to receive a kidney transplant. Instead, he was referred to the Mass General Weight Center for life-changing obesity treatment.
Adding the dietary supplements folate and vitamin B12 to treatment with antipsychotic medication improved a core symptom component of schizophrenia in a study of more than 100 patients.
A new approach to investigating hard-to-find chromosomal abnormalities has identified 33 genes associated with autism and related disorders, 22 for the first time. Several of these genes also appear...
As science has attempted to accommodate women’s desire to prolong their childbearing years, men have tended to worry much less about the ticking of their biological clocks. But new research from...
Dietary therapy is prescribed most often for patients with refractory epilepsy, whose seizures have not been controlled despite trying multiple antiepileptic drugs.
For newlyweds Peter Mundel, MD, and Anna Greka, MD, PhD, the most wonderful wedding gift was learning that a paper they co-authored was accepted by the New England Journal of Medicine (NEJM). Greka...
One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop...
Brain studies suggest that doctors learn to suppress normal responses to patients’ suffering.
A new investigational drug significantly reduced urinary cortisol levels and improved symptoms of Cushing's disease in the largest clinical study of this endocrine disorder ever conducted.
David Cournoyeris actually happy he is gaining weight. The 57-year-old North Attleboro, Mass., resident sees it as a benchmark of success after undergoing a per-oral endoscopic myotomy (POEM), a new...
For four years, Benard Basant didn’t know what it was like to breathe fresh air. Born with a congenital heart disease that eventually affected his lungs, the 36-year-old Connecticut resident was...
Human corneal endothelial cells (HCEnCs) form a monolayer of hexagonal cells whose main function is to maintain corneal clarity by regulating corneal hydration. Cell loss due to aging or corneal...
Massachusetts General Hospital's Merit Cudkowicz discovered a key to jumpstarting ALS research: pooling resources.
MassGeneral Hospital for Children’s Food Allergy Center experts share their surefire tips for ensuring families with food allergies experience a happy and healthy holiday season.
Patients seeking relief from gastroesophageal reflux disease (GERD) have a new treatment option to consider based on an innovative use of magnets. Mass General is the first and only hospital in New...
Is aging inevitable? What factors make older tissues less able to maintain and repair themselves? A new study from MGH investigators and collaborators at King's College London describes how muscle...
MGH researchers have identified a gene variant that helps predict how much weight an individual will lose after gastric bypass surgery, a finding with the potential both to guide treatment planning...
Why do some people take their own lives—as many as 36,000 each year in the United States alone—and why do warning signs go unheeded? Though suicide is the 10th leading cause of death in the United...
A strategy developed by Massachusetts General Hospital (MGH)-based investigators to increase levels of beneficial high-density lipoprotein (HDL) has been shown for the first time to be effective in...
A drug approved for the treatment of rheumatoid arthritis may also turn out to be the first targeted therapy for one of the most common forms of kidney disease, a condition that almost inevitably...
Being part of the Mass General Research Scholars Program has helped Galit Alter, PhD, advance her work and attract the attention of major funding agencies.
At Massachusetts General Hospital, scientists have long understood the potential of egg freezing for women who want to preserve their fertility.
Like many innovations in medicine, this discovery began as a problem. In the early 1990s, radiologists began using positron emission tomography, a type of body-scanning technology, to hunt for...
A search for genes that change their levels of expression in response to starvation has uncovered potential clues to the mechanism behind the health benefits of omega fatty acids. MGH researchers...

Pages