Massachusetts General

Transcending the disciplines of microbiology, molecular and cell biology, and physiology, Dr. Alessio Fasano’s research focuses on the mucosal biology of the gut. By focusing on the “cross talk”...
A team led by MGH researchers has identified a genetic signature that may reflect the risk of tumor recurrence or spread in men surgically treated for prostate cancer. If confirmed, the genetic risk...
The initial assessment of a blood test to help diagnose major depressive disorder indicates it may become a useful clinical tool. A team including MGH researchers reports that analyzing levels of...
Specially designed comprehensive behavioral therapy is more effective than sessions offering patient support and education in helping adults with Tourette syndrome manage their tics – sudden,...
Bioengineered rat kidneys developed by Massachusetts General Hospital (MGH) investigators successfully produced urine both in a laboratory apparatus and after being transplanted into living animals...
Finding solutions to global health problems affecting some of the world's poorest regions is a key goal of CAMTech, says Elizabeth Bailey, director of the Mass General-based organization.
Research laboratories at Massachusetts General Hospital are in the midst of a revolution and computational biology is the catalyst.
Patients with food allergy have a sensitization to a specific food or foods and manifest a reproducible immune response whenever exposed to food-based allergens. The true prevalence of food allergy...
Massachusetts General Hospital research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some...
MGH researchers and their colleagues have used digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid of patients with brain...
For George Velmahos, MD, Mass General’s chief of Trauma Surgery, caring for victims of the April 15 Boston Marathon bombings underscored the importance of the research he has pursued for years. Dr...
MGH researchers have identified what may be a major factor behind the increased risk of two adverse outcomes in IVF pregnancies – extremely high estrogen levels at the time of embryo transfer. They...
An assay designed to measure normal and abnormal forms of the huntingtin protein – the mutated form of which causes Huntington's disease – was successful in detecting levels of the mutant protein in...
Massachusetts General Hospital (MGH) investigators have described what may be a newly identified disease that appears to explain some cases of widespread chronic pain and other symptoms in children...
Could taking a run or going for a swim be an effective alternative to drug therapy in treating depression? In one recent experiment, Madhukar H. Trivedi, professor of psychiatry and director of the...
Inflammatory Bowel Disease (IBD) can be a complex disease to treat. As part of Massachusetts General Hospital's multidisciplinary approach for IBD management, patients receive treatment from an...
Researchers at the Massachusetts General Hospital Institute for Heart, Vascular and Stroke Care and Vanderbilt Heart and Vascular Institute have found a chemical biomarker in blood that can predict...
Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for...
David Rattner, MD, chief of the Division of Gastrointestinal and General Surgery at the Mass General Digestive Healthcare Center, answers frequently asked questions (FAQ) about the LINX® Reflux...
Recent work at the MassGeneral for Hospital Children’s Developmental Immunology Program reveals potential therapeutic targets for staph-related infections, inflammatory bowel disease, Alzheimer’s...
Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate...
As the nation’s healthcare system strains to manage a sour economy and an aging population, large academic medical centers like Massachusetts General Hospital are on the hot seat to cut costs. In the...
BOSTON – For the first time, Massachusetts General Hospital (MGH) researchers have isolated egg-producing stem cells from the ovaries of reproductive age women and shown these cells can produce what...
The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis – blocking production of a mutant protein that causes an inherited form of the progressive neurodegenerative...
MGH investigators have determined that one of the recently identified genes contributing to the risk of late-onset Alzheimer's disease regulates the clearance of the toxic amyloid beta (A-beta)...
Thomas Gagnon arrived at Massachusetts General Hospital expecting to receive a kidney transplant. Instead, he was referred to the Mass General Weight Center for life-changing obesity treatment.
Adding the dietary supplements folate and vitamin B12 to treatment with antipsychotic medication improved a core symptom component of schizophrenia in a study of more than 100 patients.
A new approach to investigating hard-to-find chromosomal abnormalities has identified 33 genes associated with autism and related disorders, 22 for the first time. Several of these genes also appear...
As science has attempted to accommodate women’s desire to prolong their childbearing years, men have tended to worry much less about the ticking of their biological clocks. But new research from...
Dietary therapy is prescribed most often for patients with refractory epilepsy, whose seizures have not been controlled despite trying multiple antiepileptic drugs.

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