Massachusetts General

MassGeneral Hospital for Children’s Food Allergy Center experts share their surefire tips for ensuring families with food allergies experience a happy and healthy holiday season.
Patients with food allergy have a sensitization to a specific food or foods and manifest a reproducible immune response whenever exposed to food-based allergens. The true prevalence of food allergy...
For four years, Benard Basant didn’t know what it was like to breathe fresh air. Born with a congenital heart disease that eventually affected his lungs, the 36-year-old Connecticut resident was...
Throughout the month of February, our doctors and specialists in the Massachusetts General Hospital Institute for Heart, Vascular and Stroke Care will be sharing their expertise on various heart...
Massachusetts General Hospital research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some...
Researchers at the Massachusetts General Hospital Institute for Heart, Vascular and Stroke Care and Vanderbilt Heart and Vascular Institute have found a chemical biomarker in blood that can predict...
A phase I clinical trial has confirmed that use of a generic vaccine to raise levels of an immune system modulator can cause the death of autoimmune cells targeting the insulin-secreting cells of the...
One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop...
Like many innovations in medicine, this discovery began as a problem. In the early 1990s, radiologists began using positron emission tomography, a type of body-scanning technology, to hunt for...
As the nation’s healthcare system strains to manage a sour economy and an aging population, large academic medical centers like Massachusetts General Hospital are on the hot seat to cut costs. In the...
A new investigational drug significantly reduced urinary cortisol levels and improved symptoms of Cushing's disease in the largest clinical study of this endocrine disorder ever conducted.
David Rattner, MD, chief of the Division of Gastrointestinal and General Surgery at the Mass General Digestive Healthcare Center, answers frequently asked questions (FAQ) about the LINX® Reflux...
A 72-year-old patient is losing weight. His primary care provider believes the cause may be a stomach virus he recently contracted, but it is hard to be certain – the weight loss has been gradual,...
Is aging inevitable? What factors make older tissues less able to maintain and repair themselves? A new study from MGH investigators and collaborators at King's College London describes how muscle...
For newlyweds Peter Mundel, MD, and Anna Greka, MD, PhD, the most wonderful wedding gift was learning that a paper they co-authored was accepted by the New England Journal of Medicine (NEJM). Greka...
Bioengineered rat kidneys developed by Massachusetts General Hospital (MGH) investigators successfully produced urine both in a laboratory apparatus and after being transplanted into living animals...
An assay designed to measure normal and abnormal forms of the huntingtin protein – the mutated form of which causes Huntington's disease – was successful in detecting levels of the mutant protein in...
The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis – blocking production of a mutant protein that causes an inherited form of the progressive neurodegenerative...
Massachusetts General Hospital (MGH) investigators have described what may be a newly identified disease that appears to explain some cases of widespread chronic pain and other symptoms in children...
Anne Louise Oaklander, MD, PhD, associate professor of Neurology, says shingles and post-herpetic neuralgia (PHN), a serious neurological complication in which pain lingers in an area of previous...
About half of a small group of patients with fibromyalgia – a common syndrome that causes chronic pain and other symptoms – was found to have damage to nerve fibers in their skin and other evidence...
MGH researchers and their colleagues have used digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid of patients with brain...
Dietary therapy is prescribed most often for patients with refractory epilepsy, whose seizures have not been controlled despite trying multiple antiepileptic drugs.
A drug approved for the treatment of rheumatoid arthritis may also turn out to be the first targeted therapy for one of the most common forms of kidney disease, a condition that almost inevitably...
MGH researchers have identified what may be a major factor behind the increased risk of two adverse outcomes in IVF pregnancies – extremely high estrogen levels at the time of embryo transfer. They...
Watching Wyatt Joyner wiggle and bounce in his mom’s lap, it is difficult to imagine that the 9-month-old – now nearly the size of his 2-year-old sister – was once in the Newborn Intensive Care Unit...
As science has attempted to accommodate women’s desire to prolong their childbearing years, men have tended to worry much less about the ticking of their biological clocks. But new research from...
MGH investigators have determined that one of the recently identified genes contributing to the risk of late-onset Alzheimer's disease regulates the clearance of the toxic amyloid beta (A-beta)...
Mark Albers, MD, PhD, is developing a set of simple but powerful tools that examine the cognitive processing of odors to screen for the very earliest stages of preclinical Alzheimer’s Disease. “...
A search for genes that change their levels of expression in response to starvation has uncovered potential clues to the mechanism behind the health benefits of omega fatty acids. MGH researchers...

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