Set on the Bosphorus strait, at the crossroads of Asia and Europe, the Shangri-La Bosphorus Hotel, Istanbul (+90.212.275.8888, www.shangri-la.com), blends the best of East and West. The hotel, which the Hong Kong–based Shangri-La Group unveiled last May, occupies a newly built neoclassical-style structure on the European side of the Turkish city. The property displays more than 1,000 pieces of European and Asian art, including a 59-foot-long Chinese silk painting and a Bohemian crystal chandelier. Inside the 186 guest rooms, bespoke furnishings in understated blue and beige tones create a modern ambience; 17 suites, most with private terraces, provide the best views of the Bosphorus. Istanbul’s duality is most pronounced at the hotel’s Ist Too, which serves sushi, Cantonese fare, and Mediterranean cuisine in various dining areas. The Chi Spa offers relaxing Balinese therapies, an authentic Turkish hammam, and a Roman-bath-style pool. ($380–$2,575).