TIMOTHY GOWER

Same Genes, Different Fates

Eppie Lederer and Pauline Phillips were one of the most famous pairs of identical twins in the United States during the 20th century. Born 17 minutes apart, both women became wildly popular syndicated columnists—as Ann Landers and Abigail Van Buren, respectively—and dispensed tart-tongued advice about love and other matters. Photos from their younger days reveal […]

The Off-Label Debate

About one in five prescriptions is “off label”—that is, a drug prescribed to treat a condition for which it hasn’t been approved by the Food and Drug Administration. That’s a legal option for physicians, and it’s frequently a necessary one. Certain populations (notably children, pregnant women and the elderly) often aren’t included in trials needed […]