A couple of hours southeast, the Edwin is an Autograph Collection hotel that opened in October. And it has kicked Chattanooga’s fledgling hospitality scene into high gear. Though the 90-room property is part of a larger management group, nothing about it screams hotel chain (as is the case with a few others on this list, too). Instead, every aspect of the Edwin has been carefully tied to the local culture: 200 pieces of artwork from Chattanooga-area artists hang proudly throughout, the Whitebird restaurant serves progressive Appalachian cuisine from chef Kevin Koroman, and partnerships with local institutions like the Hunter Museum of American Art and Chattanooga Whiskey ensure you’ll have easy access to the best the city has to offer. No matter how you spend your days exploring, don’t miss evenings up on the rooftop at Whiskey Thief, where you can sip classically southern cocktails while taking in views of the Tennessee River and the Cumberland Plateau.